欧博百家乐vncg (urinary bladder route)
Description
Nadofaragene Firadenovec-vncg is used to treat patients with high-risk Bacillus Calmette-Guerin (BCG)-unresponsive, non-muscle invasive bladder cancer (NMIBC) with a tumor type called carcinoma in situ (CIS) with or without papillary tumors.
This medicine is to be used only by or under the direct supervision of a doctor.
This product is available in the following dosage forms:
Suspension
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of Adstiladrin® in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Adstiladrin® in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Bacillus of Calmette and Guerin Vaccine, Live
Dengue Tetravalent Vaccine, Live
Measles Virus Vaccine, Live
Mumps Virus Vaccine, Live
Rubella Virus Vaccine, Live
Smallpox Monkeypox Vaccine
Typhoid Vaccine
Varicella Virus Vaccine, Live
Yellow Fever Vaccine
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Adenovirus Vaccine Type 4, Live
Adenovirus Vaccine Type 7, Live
Cholera Vaccine
Ebola Zaire Vaccine, Live
Influenza Virus Vaccine, Live
Rotavirus Vaccine, Live
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Immune system problems—Use with caution. May increase risk for infection.
Proper Use
A nurse or other trained health professional will give you this medicine in a hospital or clinic. This medicine is given through a tube (catheter) that is placed into your bladder once every 3 months.
This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.
Your doctor will give you other medicine (eg, an anticholinergic) before you receive this medicine.
Precautions
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests will be needed to check for unwanted effects.
If you can get pregnant, your doctor may do tests to make sure you are not pregnant before starting this medicine. Using this medicine while you are pregnant can harm your unborn baby. Female patients should use an effective form of birth control during treatment and for at least 6 months after the last dose. Male patients who have female partners should use an effective form of birth control during treatment and for at least 3 months after the last dose If you think you have become pregnant while using this medicine, tell your doctor right away.
Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Blood in the urine
burning while urinating
chills
difficult or painful urination
fever
trouble in holding or releasing urine
unusual tiredness or weakness
Less common
Anxiety
arm, back, or jaw pain
blurred vision
chest pain, discomfort, heaviness, or tightness
cold sweats
coma
confusion
cool, pale skin
decreased urination
depression
dizziness
dry mouth
fainting
fast or irregular heartbeat
headache
lightheadedness
nausea
nervousness
nightmares
rapid breathing
seizures
shakiness
slurred speech
sunken eyes
sweating
thirst
trouble breathing
wrinkled skin
Rare
Dilated neck veins
blue or pale skin
irregular breathing
problems with movement, walking, or speech
swelling of the face, fingers, feet, or lower legs
vomiting
weight gain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.